Antimicrobial and Phytochemical Analysis of Turmeric Powder Extract

Medicinal plants are a rich source of numerous pharmacologically active molecules. Scientists are currently focusing on the phytochemicals to treat numerous maladies affecting mankind. Curcuma longa (Turmeric) a rhizomatous perennial plant belonging to family Zingiberaceae is widely used as a food additive and as traditional medicine for treating various ailments. It has anti-inflammatory, antifungal, antimicrobial, virucidal, antimutagenic and antioxidant properties. The purpose of the study was to do preliminary phytochemical screening of the extracts of the turmeric rhizome and investigate its antimicrobial activity.100 g of powdered turmeric rhizome was extracted with MEOH: DCM (ratio 1:1) by cold percolation for 72 hours. The extract was concentrated using Rotavapor and dried. The residue yielded a reddish brown sticky mass. The yield was 11% w/w. The crude extract was subjected to silica gel column chromatography and isolated compounds subjected to preliminary phytochemical analysis.

 The antibacterial potential of two extracts of Curcuma longa against pathogenic bacteria such as Staphylococcus aureus and Escherichia coli were evaluated by agar well diffusion method.                                 All the plant extracts showed activity with MEOH: DCM extract exhibiting high activity against the reference strains used.

Keywords: Antimicrobial activity; phytochemical screening; Curcuma longa

Documentation :